Neil Patrick Harris plays Henry Coltrane in It’s A Sin (Picture: Channel 4)

It’s A Sin bosses were blessed with a case of good timing when it came to casting Neil Patrick Harris in the Channel 4 drama.

The How I Met Your Mother star plays Henry Coltrane in the five-part limited series from Russell T Davies, which tells the story of a group of friends amid the Aids pandemic in the UK in the 1980s.