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Peptides are multitasking chains of amino acids that are naturally occurring in the body, but within the best peptide creams, can be combined to do the absolute most for your skin—protecting its upper layer, ramping up collagen and elastin production, accelerating wound healing, and so much more. People usually look to peptides specifically, though, for their ability to smooth over fine lines. They've long been touted as a non-invasive, topical way to emulate injectable-like results.