LONDON, Jan 11 — Crystal Palace suffered the biggest shock in FA Cup history as the holders suffered a humiliating 2-1 defeat at sixth-tier Macclesfield, while Chelsea manager Liam Rosenior started his reign with a 5-1 rout of Charlton yesterday.

Antoine Semenyo began his Manchester City career by scoring in a 10-1 rout of Exeter, but Tottenham boss Thomas Frank’s future was plunged into doubt after a 2-1 loss to Aston Villa.