Alphabet Inc must lift restrictions that prevent developers from setting up rival marketplaces and billing systems that compete with its Google Play Store, a judge ruled, upending the search giant’s dominance in the lucrative Android app market and probably denting its revenue.

A US federal judge in San Francisco on Monday handed a big victory to Epic Games Inc. in its long-running challenge to the technology giant’s app store, another antitrust blow to Google following its recent major defeat in one US Justice Department case and while it’s still fighting another.