Over the past 22 years, one of daytime's longest-running talk shows has had numerous names: Live With Regis and Kelly; Live! With Kelly; Live With Kelly and Michael; Live! With Kelly (again); Live With Kelly and Ryan; and starting Monday, Live With Kelly and Mark.

Kelly Ripa has been the on-air constant of the popular series during those two-plus decades, steering the ship after the departure of Regis Philbin in 2011. She even held down the fort twice by herself (with rotating guest hosts) before a four-year stretch with Michael Strahan, and then for a year before Ryan Seacrest joined her — but the American Idol and radio-show host bid farewell to Live on Friday.