Pope Francis, looking frail and with belabored breathing that made it difficult for him to speak, made his first appearance in more than six weeks Sunday, appearing briefly on the balcony of a Rome hospital to greet hundreds of people gathered in the square in front.

“Thank you, everyone,” he said in a wisp of a voice. The pope later left the hospital to briefly stop at the Basilica of Santa Maria Maggiore, which has an icon of the Virgin Mary he is devoted to, before heading to the Vatican guesthouse where he lives.