Sophia Bush is getting candid about a difficult period. 

The One Tree Hill alum spoke out about her challenging fertility journey after tying the knot with estranged husband Grant Hughes in 2022. 

"After the wedding I found myself in the depths and heartbreak of the fertility process, which was the most clarifying experience of my life," Sophia explained in a Glamour essay published April 25. "It feels like society is finally making space for brutally honest conversations about how hard and painful any fertility journey is, but I kept mine private."