The Amsterdam-based psychedelic retreat and practitioner training provider Synthesis Institute has filed for bankruptcy in the Netherlands, Willamette Week reported this week, leaving almost 300 students enrolled in its psilocybin facilitator training course in Oregon with an uncertain future.

Founded in the Netherlands in 2018 by Myles Katz and Martijn Schirp, Synthesis Institute sought to bridge the gap between clinical and more wellness-oriented psychedelic therapies, which are used to help tackle depression and anxiety and has shown promise to help treat other mental health ailments. Its flagship center just outside of Amsterdam offered three- or five-day retreats at roughly $1,000 per day. The company started expanding to the North American market in 2021, and Synthesis planned to establish a psilocybin service center and facilitator training program. It secured $7.25 million in Series A funding in September 2021, with an unusual company structure in the form of a Steward-Ownership organization.