The romantic comedy was a Hollywood mainstay throughout the 2000s – producing household names such as Matthew McConaughey, Adam Sandler and Steve Carell to reel off just a few.

The latter seized his opportunity in the big leagues with 2005’s 40-Year-Old Virgin, in which Carell portrayed the nerdy Andy Stitzer – who, goaded by his newfound work buddies, sets out to lose his virginity at the grand age of 40.

The movie, which Carell co-wrote alongside Anchorman creator Judd Apatow, was an overwhelming success - raking in more than $177 million at the box office from a budget of $26 million. The Hollywood hit saw Carell star opposite several well-known stars today including Paul Rudd, Kevin Hart and a budding Seth Rogen.