Botic Van de Zandschulp matched the best run by any US Open qualifier in reaching the quarter-finals and hopes to shock Daniil Medvedev and equal more Grand Slam history.

The 25-year-old Dutchman upset 11th seed Diego Schwartzman of Argentina 6-3, 6-4, 5-7, 5-7, 6-1 after four hours and 20 minutes to book a last-eight match with Russian second seed Medvedev, a two-time Grand Slam runner-up.